Ocular blood flow alteration in glaucoma is related to systemic vascular dysregulation
نویسندگان
چکیده
منابع مشابه
Ocular blood flow alteration in glaucoma is related to systemic vascular dysregulation.
AIMS To investigate the source of ocular blood flow alterations in glaucoma. METHODS In 56 patients with open angle glaucoma, blood flow parameters were obtained from both eyes in the ophthalmic and central retinal artery by means of colour Doppler imaging, as well as in the choroidal circulation and the neuroretinal rim of the optic nerve by means of laser Doppler flowmetry. Based on these h...
متن کاملSystemic vascular dysregulation and retrobulbar hemodynamics in normal-tension glaucoma.
PURPOSE To investigate the influence of systemic vascular dysregulation on retrobulbar hemodynamics in normal-tension glaucoma (NTG). METHODS Forty-four untreated patients with NTG and 40 healthy controls matched for age, sex, and intraocular pressure were included. Cold-induced nailfold capillaroscopic features, mean and diastolic ocular perfusion pressures (mOPP, dOPP), endothelin-1 (ET-1) ...
متن کاملOcular Blood Flow and Normal Tension Glaucoma
Normal tension glaucoma (NTG) is known as a multifactorial optic neuropathy characterized by progressive retinal ganglion cell death and glaucomatous visual field loss, even though the intraocular pressure (IOP) does not exceed the normal range. The pathophysiology of NTG remains largely undetermined. It is hypothesized that the abnormal ocular blood flow is involved in the pathogenesis of this...
متن کاملOcular blood flow and systemic blood pressure in patients with primary open-angle glaucoma and ocular hypertension.
PURPOSE There is evidence that altered optic nerve head (ONH) blood flow may play a role in the development and progression of glaucoma. In the present study, the baseline characteristics were examined in a study population participating in a clinical trial in which the ocular hemodynamic effects of timolol and dorzolamide were compared. METHODS One hundred forty patients with primary open-an...
متن کاملOcular Blood Flow and its Determination and Relevance in Glaucoma
Received for publication October2005 .................................. Although intraocular pressure (IOP) is closely linked to the pathogenesis of primary open angle glaucoma (POAG) and reduction of IOP slows down the glaucoma damage, 12% of subjunctives with controlled IOP continue to have progressive visual field loss and about 30% of glaucoma patients never experience high IOP. Clinical ex...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 2004
ISSN: 0007-1161
DOI: 10.1136/bjo.2003.032110