منابع مشابه
Organelle relationships in cultured 3T3-L1 preadipocytes
In differentiating 3T3-L1 cells, lipid spheres, the endoplasmic reticulum (ER), microperoxisomes, and mitochondria form "constellations" that may reflect the interplay of lipid metabolizing enzymes in these organelles. ER cisternae are also situated very close to "rosettes,"plasmalemmal specializations found in mature adipocytes in vivo. As in hepatocytes and absorptive cells of the intestine, ...
متن کاملPU.1 promotes miR-191 to inhibit adipogenesis in 3T3-L1 preadipocytes.
PU.1, an Ets family transcription factor, was previously demonstrated expressed in 3T3-L1 preadipocytes and had an negative effect on adiopogenesis. However, the underlying mechanism remains elusive. Here, miR-191 was identified as an inhibitor of adipocyte differentiation through targeting the 3' untranslated regions of C/EBPβ, the initial factor in the C/EBPα/β-PPARγ terminal pathway of adipo...
متن کاملEffects of Cnidium Officinale (Makino) and Ulmus Pumila (Linne.) Extracts on Adipogenesis in 3T3-L1 Preadipocytes
Certain natural therapeutic plant extracts and bioactive compounds, which are commonly used as components of East Asian medicine, have the tendency to promote adipogenesis through preadipocyte proliferation and differentiation. In this study, methanol extracts Cnidium officinale Makino and Ulmus pumila Linne were screened for their ability to induce preadipocyte proliferation and differentiatio...
متن کاملFAM3A enhances adipogenesis of 3T3-L1 preadipocytes via activation of ATP-P2 receptor-Akt signaling pathway
FAM3A plays important roles in regulating hepatic glucose/lipid metabolism and the proliferation of VSMCs. This study determined the role and mechanism of FAM3A in the adipogenesis of 3T3-L1 preadipocytes. During the adipogenesis of 3T3-L1 preadipocytes, FAM3A expression was significantly increased. FAM3A overexpression enhanced 3T3-L1 preadipocyte adipogenesis with increased phosphorylated Akt...
متن کاملInsulin receptor synthesis and turnover in differentiating 3T3-L1 preadipocytes.
3T3-L1 "preadipocytes" can be induced to differentiate in culture into cells having the morphological and biochemical characteristics of adipocytes. The binding of 125I-insulin to the cell-surface of differentiated and undifferentiated 3T3-L1 cells and nondifferentiating 3T3-C2 cells was compared. In the absence of agents which induce adipocyte conversion, ie, insulin or insulin plus methylisob...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Nutrition
سال: 2002
ISSN: 0022-3166,1541-6100
DOI: 10.1093/jn/132.5.904