Occupational exposure to glycol ethers and ovarian function
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چکیده
منابع مشابه
Occupational exposure to glycol ethers and ovarian function.
T he simultaneously hydrophilic and lipophilic properties of glycol ethers account for their use as solvents in a wide range of industrial and domestic products, including paints, varnishes, cleaning agents, and cosmetics. These dozens of compounds are grouped into two main classes: ethylene glycol ethers (EGEs) and propylene glycol ethers (PGEs). Because animal experiments show several EGEs to...
متن کاملProposed occupational exposure limits for select ethylene glycol ethers using PBPK models and Monte Carlo simulations.
Methoxyethanol (ethylene glycol monomethyl ether, EGME), ethoxyethanol (ethylene glycol monoethyl ether, EGEE), and ethoxyethyl acetate (ethylene glycol monoethyl ether acetate, EGEEA) are all developmental toxicants in laboratory animals. Due to the imprecise nature of the exposure data in epidemiology studies of these chemicals, we relied on human and animal pharmacokinetic data, as well as a...
متن کاملMeasuring exposures to glycol ethers.
In 1981, NIOSH began investigating the potential reproductive health effects resulting from exposures to a class of organic solvents known generically as glycol ethers (GE). This research was begun as a result of the NIOSH criteria document development program which revealed little data available on the health effects of glycol ether exposure. Toxicologic research was begun by NIOSH and other r...
متن کاملGenotoxicity of glycol ethers.
The genetic toxicology of glycol ethers is reviewed. Ethylene glycol monomethyl ether (EGME) and diglyme have been more extensively studied than other members of this series. Most results indicate a lack of genotoxic potential, but certain tests have yielded positive responses with certain compounds. Ethylene glycol monoethyl ether (EGEE) induced sister chromatid exchanges and chromosomal aberr...
متن کاملOccupational Exposure to Asbestos and Ovarian Cancer: A Meta-analysis
OBJECTIVE A recent Monographs Working Group of the International Agency for Research on Cancer (IARC) concluded that there is sufficient evidence for a causal association between exposure to asbestos and ovarian cancer. We performed a meta-analysis to quantitatively evaluate this association. DATA SOURCES Searches of PubMed and unpublished data yielded a total of 18 cohort studies of women oc...
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ژورنال
عنوان ژورنال: Occupational and Environmental Medicine
سال: 2005
ISSN: 1351-0711
DOI: 10.1136/oem.2005.019901