منابع مشابه
Occupational exposure to glycol ethers and ovarian function.
T he simultaneously hydrophilic and lipophilic properties of glycol ethers account for their use as solvents in a wide range of industrial and domestic products, including paints, varnishes, cleaning agents, and cosmetics. These dozens of compounds are grouped into two main classes: ethylene glycol ethers (EGEs) and propylene glycol ethers (PGEs). Because animal experiments show several EGEs to...
متن کاملProposed occupational exposure limits for select ethylene glycol ethers using PBPK models and Monte Carlo simulations.
Methoxyethanol (ethylene glycol monomethyl ether, EGME), ethoxyethanol (ethylene glycol monoethyl ether, EGEE), and ethoxyethyl acetate (ethylene glycol monoethyl ether acetate, EGEEA) are all developmental toxicants in laboratory animals. Due to the imprecise nature of the exposure data in epidemiology studies of these chemicals, we relied on human and animal pharmacokinetic data, as well as a...
متن کاملMeasuring exposures to glycol ethers.
In 1981, NIOSH began investigating the potential reproductive health effects resulting from exposures to a class of organic solvents known generically as glycol ethers (GE). This research was begun as a result of the NIOSH criteria document development program which revealed little data available on the health effects of glycol ether exposure. Toxicologic research was begun by NIOSH and other r...
متن کاملGenotoxicity of glycol ethers.
The genetic toxicology of glycol ethers is reviewed. Ethylene glycol monomethyl ether (EGME) and diglyme have been more extensively studied than other members of this series. Most results indicate a lack of genotoxic potential, but certain tests have yielded positive responses with certain compounds. Ethylene glycol monoethyl ether (EGEE) induced sister chromatid exchanges and chromosomal aberr...
متن کاملInteractive effect of combined exposure to ethylene glycol ethers and ethanol on hematological parameters in rats
The study of the interaction of three glycol ethers, i.e. 2-methoxyethanol (ME), 2-ethoxyethanol (EE) and 2-butoxyethanol (BE) administered subcutaneously for 4 weeks and ethanol simultaneously given as 10% w/v solution for drinking in male rats, was carried out from a toxicodynamic point of view. Administered alone, ME (2.5 and 5.0 mM/kg), EE (2.5 and 5.0 mM/kg) or BE (0.75 and 1.25 mM/kg) res...
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ژورنال
عنوان ژورنال: AAOHN Journal
سال: 1994
ISSN: 0891-0162
DOI: 10.1177/216507999404200901