Occupational allergy to β-lactam antibiotics

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Occupational allergy to β-lactam antibiotics

Background Contact urticaria in atopic patients was described by Hannuksela [1], among others, in 1980. It generally appears within 30 min of allergen contact and, in the majority of cases, is restricted to the areas of contact; however, local spread and generalized urticaria in the sense of anaphylaxis are seen. Allergic rhinoconjunctivitis and asthma may also subsequently occur [2]. Von Krogh...

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Allergy to b-Lactam Antibiotics in Children

Background. Skin tests with soluble b-lactams can be used to diagnose immediate and delayed hypersensitivity (HS) reactions to b-lactam antibiotics. Very few studies have been performed with children with suspected b-lactam allergy. In these studies, immediate HS to b-lactams was diagnosed by skin tests in 4.9% to 40% of children. The diagnostic and predictive values of immediate responses in s...

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β-Lactam Antibiotics Renaissance.

Since the 1940s β-lactam antibiotics have been used to treat bacterial infections. However, emergence and dissemination of β-lactam resistance has reached the point where many marketed β-lactams no longer are clinically effective. The increasing prevalence of multidrug-resistant bacteria and the progressive withdrawal of pharmaceutical companies from antibiotic research have evoked a strong rea...

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Degradation of β-lactam antibiotics

Recent developments in the chemistry and biology of βlactam antibiotics which culminated with the introduction of several clinically useful classical and nonclassical β-lactams have been most thrilling and highly rewarding. While this review touches upon the historical development of β-lactams and their reactivity in a nutshell, it provides an overview of various aspects of chemical and enzymat...

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β-lactam allergy: clinical implications and costs

BACKGROUND β-lactam allergy is the most commonly reported medication allergy and it remains a key issue in antibiotic prescribing. A detailed and accurate history taking play a key role in preventing potentially serious clinical incidents and it may contribute in reducing costs. METHODS Data were collected for patients with a documented penicillin allergy on their drug chart during a six mont...

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ژورنال

عنوان ژورنال: Allergo Journal International

سال: 2015

ISSN: 2197-0378

DOI: 10.1007/s40629-015-0047-3