OC-0182: 2nd breast conserving therapy with interstitial BT vs mastectomy for treatment of local recurrences

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Breast-conserving therapy versus mastectomy

There is an ongoing debate regarding the use of randomised controlled trials (RCTs) versus observational studies when investigating treatment effects in clinical practice [1]. This holds especially true for the comparison of breast-conserving therapy (BCT) and mastectomy (MAST), which gained much attention since the publication of our observational study in Lancet Oncology [2]. RCTs are highly ...

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Evaluation of Local Recurrence of Breast Cancer after Mastectomy and Breast Preservation Therapy

Abstract Introduction: Breast cancer is the most common cancer among women. Even though mastectomy is known as a highly effective method to treat breast cancer, the percentage of patients with local recurrence is still high. Objective: To determine the incidence of local recurrence after mastectomy and breast preservation surgery. Materials and Methods: Patients with breast cancer that under...

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Local recurrence after mastectomy or breast-conserving surgery and radiation.

Approximately 10% to 15% of patients with stage I/II invasive breast cancer will develop a clinically isolated local recurrence. The standard management of an ipsilateral breast tumor recurrence following breast-conserving surgery and radiation is salvage mastectomy, while local excision and radiation are optimal treatment of a chest wall recurrence following initial mastectomy. Although there ...

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Comparison of Locoregional Recurrence with Mastectomy vs. Breast Conserving Surgery in Pregnancy Associated Breast Cancer (PABC)

We have compared outcomes, including the locoregional recurrence, between mastectomy and breast conserving therapy in PABC. Patients were divided into those who were treated with mastectomies (group 1) and those with breast conserving surgery (group 2). The groups were comparable except for lower mean age in group 2 and more patients with stage III disease and higher number of nodes positive in...

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True Local Recurrences or New Primary Tumors after Breast-Conserving Surgery and Radiation Therapy

Background&Aims:True local recurrences(TR)and new primary tumors(NP)in the conserved breast after breast-conserving surgery with radiation therapy are determined by the initial surgical margin,the location of recurrent tumors and the histological consistency between initial tumors and recurrent tumors. Methods:A total of 15 patients with breast recurrence out of a group of 389 women with breast...

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ژورنال

عنوان ژورنال: Radiotherapy and Oncology

سال: 2017

ISSN: 0167-8140

DOI: 10.1016/s0167-8140(17)30625-4