Obesity and respiratory infections: Does excess adiposity weigh down host defense?
نویسندگان
چکیده
منابع مشابه
Neonatal Host Defense against Staphylococcal Infections
Preterm infants are especially susceptible to late-onset sepsis that is often due to Gram-positive bacterial infections resulting in substantial morbidity and mortality. Herein, we will describe neonatal innate immunity to Staphylococcus spp. comparing differences between preterm and full-term newborns with adults. Newborn innate immunity is distinct demonstrating diminished skin integrity, imp...
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Obesity is one of the major epidemics of our time and its prevalence is only believed to increase over coming years. The detrimental effect of obesity on the risk of cardiovascular disease, diabetes and cancer has long been recognised and has subsequently impacted on public health policy across the globe. However, there are still gaps in our knowledge regarding the complex relationship between ...
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The emergence of infections caused by multi-drug resistant (MDR) pathogens pose a major burden to modern healthcare. Exacerbating this issue is the substantial decline in development of new classes of antibiotics by pharmaceutical companies. This has led to renewed interest in the therapeutic potential of natural anti-infective agents such as host defense peptides (HDPs). The broad antimicrobia...
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ژورنال
عنوان ژورنال: Pulmonary Pharmacology & Therapeutics
سال: 2013
ISSN: 1094-5539
DOI: 10.1016/j.pupt.2012.04.006