O12-1 A novel gene-prediction model, virtual sequencing with deep learning to predict gene alterations in colorectal cancer

The SCRUM-Japan Genesis Project aims to establish a novel algorithm, named Virtual Sequencing (VSQ), by synergistically fusing deep learning (DL) technology and pathological diagnostics for the prediction of cancer genome abnormalities. This was achieved elucidating association between morphological findings genetic abnormalities, including BRAF V600E mutations Microsatellite Instability (MSI) status directly linked therapeutic strategies advanced colorectal (CRC) patients (pts).