O1 Rheumatoid factor and Anti-CCP in rheumatoid arthritis

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Evaluation of Salivary Anti-Ccp in Rheumatoid Arthritis Patients

Aim and objective: The aimof this study was to evaluate the levels of salivary anti-cyclic citrullinated peptide (anti-CCP) in Rheumatoid Arthritis patients. The salivary anti-CCP level was compared with the serum values. Materials and method: saliva and serum samples were collected from 30 rheumatoid arthritis (group R) patients and 30 controls (group C). The samples were analysed by chemilumi...

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BACKGROUND The presence of anti-cyclic citrullinated peptide autoantibody is highly specific for rheumatoid arthritis. Certain HLA-DR4 (HLA-DRB1*04) alleles, also known as the "shared epitope," are associated with increased susceptibility to RA. In addition, these alleles may also have relevance for disease outcome. Anti-CCP antibody positivity has been associated with the presence of HLA-DR4 a...

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ژورنال

عنوان ژورنال: Indian Journal of Rheumatology

سال: 2007

ISSN: 0973-3698

DOI: 10.1016/s0973-3698(10)60316-0