O-172 Room and directions for improvement in oocyte cryopreservation
نویسندگان
چکیده
Abstract Cryopreservation and more specifically oocyte vitrification has become a before after in the field of Assisted Reproduction Techniques. Despite great efforts to improve slow freezing protocols, levels reproducibility, survival rates clinical outcomes achieved by have never been reached any these old approaches. However, once this barrier was overcome, new challenges emerged. We must reassert ourselves on issues such as efficacy, efficiency safety technique that is now fully implemented IVF laboratories around world. Continuos monitoring improvement part quality management system mandatory, keep standards qualilty, identify factors may affect look for room improvemnt finetune protocols. But also it important provide answers women who wish preserve their fertility medical or non-medical reasons. They key questions how many oocytes store, what rate will be warming, cryopreserved able fertilize develop good fresh counterparts, does number used cumulative live birth rate? Also undergoing ART, represent successful strategy. For example, patients with low response at risk ovarian hyperstimulation, two sides coin, benefit from cryopreservation. The former, storing accumulating allow them obtain success comparable those normal responders while avoiding adverse effects response; latter, postponing insemination over time, investing safety. Yet embryo can offer alternatives so both options explored compared Trial registration XXXX
منابع مشابه
Oocyte cryopreservation.
OBJECTIVE To review historical and contemporary advances in oocyte-cryopreservation techniques and outcomes. DESIGN Publications related to oocyte cryopreservation were identified through MEDLINE and other bibliographic databases. CONCLUSION(S) Oocyte cryopreservation can be used as an adjunct to conventional IVF and as an option for fertile women to electively cryopreserve their gametes. R...
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The technology so far applied clinically has been based directly on traditional human embryo cryopreservation protocols, and has produced relatively few offspring. Fortunately to date, no abnormalities have been reported from these pregnancies, regardless of the persistent concerns that freezing and thawing of mature oocytes may disrupt the meiotic spindle and thus increase the potential for an...
متن کاملHuman oocyte cryopreservation.
The clinical role of oocyte cryopreservation in assisted reproduction, as an adjunct to sperm and embryo cryopreservation, has been comparatively slow to evolve as a consequence of theoretical concerns related to efficacy and safety. Basic biological studies in the 1990's alleviated many of these concerns leading to more widespread adoption of the technology. While a number of babies were born ...
متن کاملNanoliter droplet vitrification for oocyte cryopreservation.
AIM Oocyte cryopreservation remains largely experimental, with live birth rates of only 2-4% per thawed oocyte. In this study, we present a nanoliter droplet technology for oocyte vitrification. MATERIALS & METHODS An ejector-based droplet vitrification system was designed to continuously cryopreserve oocytes in nanoliter droplets. Oocyte survival rates, morphologies and parthenogenetic devel...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2023
ISSN: ['1460-2350', '0268-1161']
DOI: https://doi.org/10.1093/humrep/dead093.209