O-095. Cytotoxic drugs: gonadal toxicity and reversal of toxicity

Mitochondrial toxicity of drugs

my expression of gratitude for giving me the possibility to work on a doctoral thesis in your lab. It has been very interesting to work under the guidance of such a motivating and inspiring person as you. I also would like to thank you for your support in times when everything did not turn out as planned. In the very first year of my thesis I was very fortunate to be guided by Dr. Michael Török...

Drugs containing halogen atoms: toxicity and lack of toxicity.

Toxicity Screening of Therapeutic Drugs

INTRODUCTION In the course of in vitro systems search for the toxicity screening of therapeutic drugs (TDs), different cellular models have been applied to examine their adverse effects in isolated organs. This article describes a simple method to determine effects of TDs at the cell membrane level. The cell membrane is an assembly of proteins and lipids that separate inside from outside, prote...

Fluids are drugs: type, dose and toxicity.

PURPOSE OF REVIEW We discuss the formulation of a prescription for intravenous (i.v.) fluid therapy (a 'volume prescription') for critically ill patients: pros/cons of different fluid types; accurate dosing; and qualitative and quantitative toxicities. Updated physiologic concepts are invoked and results of recent major clinical trials on i.v. fluid therapy in the acutely ill are interpreted. ...

Anti-tuberculosis drugs and liver toxicity.