Nutrigenomics and Systems Biology

Nutrigenomics and systems biology.

Systems biology has emerged as a critical concept for biological and medical research. Its growing recognition stems from the reality that organisms exist as systems, and the better we understand the interactions in these complex biological networks, the more readily we can develop effective prevention or treatment strategies that comprehensively address health problems. The field of systems bi...

Nutrigenomics: exploiting systems biology in the nutrition and health arenas.

Nutritional sciences are discovering the application of the so-called "omics" sciences. Propelled by the recent unravelling of the human genome and the coinciding technological developments, genotyping, transcriptomics, proteomics and metabolomics are now available to nutritional research. In the future we are likely to see new screening tools for the selection of bioactive nutrients, new bioma...

2 Cancer Biology and Nutrigenomics

Key Points 1. Current cancer models comprise those that are inherited through the germline and represent only ∼5% of total cases of human cancers. These tumors originate because of mutational events. The remaining ∼95% originate as sporadic events and evolve as a result of exposure to the environment, which includes exposure to both environmental contaminants and dietary agents. 2. The multista...

Nutrigenetics and Nutrigenomics Basel

Nutrigenetics, Nutrigenomics, and Selenium

Selenium (Se) is an important micronutrient that, as a component of selenoproteins, influences oxidative and inflammatory processes. Its' levels vary considerably, with different ethnic and geographic population groups showing varied conditions, ranging from frank Se deficiencies to toxic effects. An optimum Se level is essential for the maintenance of homeostasis, and this optimum may vary acc...