Nutrient Stress–Dysregulated Antisense lncRNA GLS-AS Impairs GLS-Mediated Metabolism and Represses Pancreatic Cancer Progression
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Sensitivity of GLS estimators in random effects models
This paper studies the sensitivity of random effects estimators in the one-way error component regression model. Maddala and Mount (1973) give simulation evidence that in random effects models the properties of the feasible GLS estimator β̂ are not affected by the choice of the first-step estimator θ̄ used for the covariance matrix. Taylor (1980) gives a theoretical example of this effect. This p...
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متن کاملExpression of Gls and Gls2 glutaminase isoforms in astrocytes.
The expression of glutaminase in glial cells has been a controversial issue and matter of debate for many years. Actually, glutaminase is essentially considered as a neuronal marker in brain. Astrocytes are endowed with efficient and high capacity transport systems to recapture synaptic glutamate which seems to be consistent with the absence of glutaminase in these glial cells. In this work, a ...
متن کاملA novel lncRNA uc.134 represses hepatocellular carcinoma progression by inhibiting CUL4A-mediated ubiquitination of LATS1
BACKGROUND Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, and tumor recurrence and metastasis are major factors that contribute to the poor outcome of patients with HCC. Long noncoding RNAs (lncRNAs) are known to regulate different tumorigenic processes, and a growing body of evidence indicates that Hippo kinase signaling is inactivated in many cancers. However...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2018
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-18-0419