Nucleotide sequences of mouse histone genes H2A and H3.1
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منابع مشابه
Nucleotide sequences of mouse histone genes H2A and H3.1.
A mouse testicular cDNA library in XgtlO was screened with a human H3 gene probe. A recombinant phage with a 5 kb insert was isolated. It contains two histone coding sequences (H2A and H3.1, 1.75 kb apart, same orientation) and begins immediately upstream of the H2A coding sequence. Since both sequences show consensus 3' elements and since the H3 gene is preceded by CCAAT and TATA motifs (conse...
متن کاملThe coding sequences of mouse H2A and H3 histone genes contains a conserved seven nucleotide element that interacts with nuclear factors and is necessary for normal expression.
Expression of replication-dependent histone genes of all classes is up-regulated coordinately at the onset of DNA synthesis. The cellular signals involved in coordinate regulation of these genes are not known. Here we report identification of an alpha element, present within the mouse histone coding region activating sequence (CRAS). We show evidence that this element is present in histone gene...
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Two histone H4 genes (Fig. 1) were Isolated from a BALB.A2G-MX mouse genomlc DNA library In lambda EMBL3 (Hug et al. (1988) Mol.Cell.BIol. 8, 3065-3079). The gene on done 12 has a 5' noncoding region of only 9 nudeotldes. The stem of the 3'-termlnal palindrome of the done 53 H4 gene has the unusual sequence GGTCCT. In both genes (as well as In all other published vertebrate H4 genes), the promo...
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Analysis of cloned sequences for yeast histone genes H2A and H2B reveals that there are only two copies of this pair of genes within the haploid yeast genome. Within each copy, the genes for H2A and H2B are separated by approximately 700 bp of spacer DNA. The two copies are separated from one another in the yeast genome by a minimum distance of 35-60 kb. Sequence homology between the two copies...
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Histone H2A is a component of eukaryotic chromatin whose expression has not been studied in plants. We isolated and characterized a tomato and a pea cDNA encoding histone H2A. We found that in tomato H2A is encoded by a small gene family and that both the pea and the tomato mRNAs are polyadenylated. Tomato H2A has 82% amino acid residue identity to pea H2A, 83% to wheat, and 65% to human and ye...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1989
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/17.21.8861