Nucleotide sequence of cDNA containing the complete coding sequence for human lysosomal glucocerebrosidase.
نویسندگان
چکیده
منابع مشابه
Molecular cloning and nucleotide sequence of human glucocerebrosidase cDNA.
Mutations in the human glucocerebrosidase gene cause Gaucher disease. A cDNA clone containing the entire human glucocerebrosidase coding region from normal cells has been isolated using lambda gt11 expression libraries. The complete nucleotide sequence, a restriction map, and a hydropathy profile are presented. Hybridization to chromosome-specific DNA localizes the human glucocerebrosidase gene...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1986
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(17)42428-8