Nucleosome Chiral Transition under Positive Torsional Stress in Single Chromatin Fibers
نویسندگان
چکیده
منابع مشابه
Nucleosome chiral transition under positive torsional stress in single chromatin fibers.
Using magnetic tweezers to investigate the mechanical response of single chromatin fibers, we show that fibers submitted to large positive torsion transiently trap positive turns at a rate of one turn per nucleosome. A comparison with the response of fibers of tetrasomes (the [H3-H4](2) tetramer bound with approximately 50 bp of DNA) obtained by depletion of H2A-H2B dimers suggests that the tra...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 2007
ISSN: 1097-2765
DOI: 10.1016/j.molcel.2007.05.037