Nucleophile Assisting Leaving Groups: A Strategy for Aliphatic 18F-Fluorination
نویسندگان
چکیده
منابع مشابه
Nucleophile assisting leaving groups: a strategy for aliphatic 18F-fluorination.
A series of arylsulfonate nucleophile assisting leaving groups (NALGs) were prepared in which the metal chelating unit is attached to the aryl ring via an ether linker. These NALGs exhibited significant rate enhancements in halogenation reactions using metal halides. Studies with a NALG containing a macrocyclic ether unit suggest that rate enhancements of these nucleophilic halogenation reactio...
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ژورنال
عنوان ژورنال: The Journal of Organic Chemistry
سال: 2009
ISSN: 0022-3263,1520-6904
DOI: 10.1021/jo900700j