Nucleolar Ultrastructure in Psoriatic Skin Lesions

The ultrastructure of Bowen's disease: nuclear and nucleolar lesions.

electron microscopic procedures to provide more information on the fine structure of nuclei and nucleoli in giant cells. Nuclei of giant cells were characterized by the presence of an increased number of interchromatinic and perichromatinic granules. In addition, dense globular structures about 500 to 1500 A in diameter were noted in association with chromatin. The spherical clusters observed i...

Psoriatic skin lesions induced by tumor-necrosis-factor-alpha-therapy

A 46-year-old, caucasian woman suffering from Crohn’s disease and a 35-year-old woman suffering from ankylosing spondylitis were treated with the TNFα blocker infliximab and developed psoriasiform skin lesions. The pathophysiology of this paradoxical clinical response as a newly recognized adverse effect of TNFα antagonists is unknown. According to the literature, this type of newly triggered p...

Skin Lesions: Enhanced Expression in Psoriatic Keratinocytes in Healthy Skin and Psoriasis

Skin Lesions in Type 2 Diabetic Patients

Bachground: Skin lesions are common in type 2 diabetic patients and its association with microvascular complications been reported. Methods: In this study, 1135 type-2 diabetic patients were included and examined by a dermatologist for diabetes mellitus related skin lesions, skin infections and cutaneous complications of the treatment. Smear, culture and biopsy of the lesions were done for defi...

Malignant skin lesions in transplant recipients

Several advances in the filed of organ transplantation in last decades have resulted in significant increase in the number and methods of transplantation. In this article various aspects of organ transplantation including immunosuppressive medications, common skin tumors seen in transplant recipients, possible mechanisms involved in increased incidence of skin tumors and finally preventive meas...