Nucleolar organiser regions (AgNORs) as predictors in transitional cell bladder cancer
نویسندگان
چکیده
منابع مشابه
Interphase argyrophilic nucleolar organiser regions and nucleolar counts in transitional cell bladder tumours.
AIMS To see whether a correlation exists between clinicopathological parameters, argyrophilic nucleolar organiser regions (AgNORs), and nucleolar counts in the nuclei of tumour cells in patients with transitional cell bladder carcinoma. METHODS Paraffin wax embedded sections from a total of 62 cases of primary transitional cell bladder carcinoma were stained with the silver colloid method. Th...
متن کاملEvaluation of argyrophilic nucleolar organiser regions (AgNORs) in multiple myeloma.
AIM To investigate the prognostic value of argyrophylic nucleolar organiser regions (AgNORs) in multiple myeloma. METHODS Bone marrow aspirates from 55 newly diagnosed patients with multiple myeloma were stained with the one step AgNO3 technique. The mean number of AgNORs in each plasma cell nucleus (AgNOR count) was tested for a possible correlation with other clinical and laboratory variabl...
متن کاملComparison of Argyrophilic Nucleolar Organiser Regions (AgNORS) with Proliferating Cell Nuclear Antigen (PCNA) in Different Grades of Transitional Cell Carcinoma of Urinary Bladder
Malignancies of urinary bladder are one of the leading malignancies in the developed countries. 1 The incidence is also high in Northern Africa and Western Asia. The world wide estimate of carcinoma of urinary bladder of new cases is 261,000 annually. 2 Amongst these, more than 50,000 cases and estimate of 9500 deaths have been predicted in United States alone. 3 The incidence is three times mo...
متن کاملNucleolar organiser regions (AgNORS) in anal intraepithelial neoplasia and invasive anal squamous cell carcinoma.
AIM To evaluate the usefulness of counting nucleolar organiser region associated proteins (AgNORs) in the management of anal squamous neoplasia. METHOD Using a silver staining technique for NOR associated proteins, 32 routinely processed paraffin wax embedded sections of anal epithelium were assessed. These consisted of normal anal epithelium (n = 9), anal intraepithelial neoplasia (AIN) grad...
متن کاملNucleolar organiser regions in pathology.
Traditional approaches to pathological diagnosis include macroscopic examination and formalin fixation with the preparation of paraffin sections stained with a variety of histochemical techniques. These routine approaches however may be disappointing in the assessment of many conditions and occasionally fail to render a precise diagnosis or provide adequate prognostic information. Consequently ...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1991
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1991.478