Nucleated Red Blood Cells (NRBCs): An Unheralded Marker of Early-Onset Neonatal Sepsis
نویسندگان
چکیده
منابع مشابه
Investigation of Changes in Nucleated Red Blood Cells in Neonatal Infection
Background: Early diagnosis is paramount to the treatment of neonatal infections. Nucleated red blood cells (NRBCs) are immature erythrocytes that increase in number due to stress and hypoxia. This study was conducted to determine NRBC count in the peripheral blood and examine its significance as a marker of neonatal infection. Methods: This case-control study was conducted on 154 infants (78 ...
متن کاملAssociation between umbilical cord blood laboratory findings with early onset neonatal sepsis
Backgrounds: Finding an efficient biomarker or combination of them as predictors of early-onset neonatal sepsis is very important. On the other hand, the use of umbilical cord blood samples in laboratory tests, along with its simplicity and availability, reflects neonate metabolic status. Background and Aim: The aim of this study was to investigate the association between umbilical cord bloo...
متن کاملA microfluidics approach for the isolation of nucleated red blood cells (NRBCs) from the peripheral blood of pregnant women.
OBJECTIVE Nucleated red blood cells (NRBCs) have been identified in maternal circulation and potentially provide a resource for the monitoring and diagnosis of maternal, fetal, and neonatal health and disease. Past strategies used to isolate and enrich for NRBCs are limited to complex approaches that result in low recovery and less than optimal cell purity. Here we report the development of a h...
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BACKGROUND Since the 1990s, finding the most efficient markers or combinations as predictors of early-onset neonatal sepsis has been the hot topic of studies. But there is no review of such biomarkers detected in umbilical blood at birth. By comparing clinical values of common inflammatory markers detected in cord blood shortly after birth, in this study we tried to find the most performing one...
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Background and objective: Neonatal sepsis is defined as presence of clinical signs accompanied by positive blood culture in newborns less than one month of age. Sepsis is a common cause of hospital admission in neonates, and it is known as one of the main causes of mortality among them, not only in developed countries but in developing ones. Delay in diagnosis and appropriate antibiotic therapy...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1999
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199904020-01623