Nuclear surveillance of RNA polymerase II transcripts
نویسندگان
چکیده
منابع مشابه
The nuclear RNA polymerase II surveillance system targets polymerase III transcripts
A key question in nuclear RNA surveillance is how target RNAs are recognized. To address this, we identified in vivo binding sites for nuclear RNA surveillance factors, Nrd1, Nab3 and the Trf4/5–Air1/2–Mtr4 polyadenylation (TRAMP) complex poly(A) polymerase Trf4, by UV crosslinking. Hit clusters were reproducibly found over known binding sites on small nucleolar RNAs (snoRNAs), pre-mRNAs and cr...
متن کاملExplorer The nuclear RNA polymerase II surveillance system targets polymerase III transcripts
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ژورنال
عنوان ژورنال: RNA Biology
سال: 2008
ISSN: 1547-6286,1555-8584
DOI: 10.4161/rna.7162