Nuclear Respiratory Factor 1 Drives Hepatocellular Carcinoma Progression by Forming a Positive Feedback Loop with LPCAT1-ERK1/2-CREB Axis
نویسندگان
چکیده
منابع مشابه
A Positive TGF-β/c-KIT Feedback Loop Drives Tumor Progression in Advanced Primary Liver Cancer12
UNLABELLED Hepatocellular carcinoma (HCC) is globally the second most common cause of cancer mortality. The majority of HCC patients are diagnosed at advanced stage disease for which no curative treatments exist. TGF-β has been identified as a potential therapeutic target. However, the molecular mechanisms mediating its functional switch from a tumor suppressor to tumor promoter in HCC and its ...
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ژورنال
عنوان ژورنال: Social Science Research Network
سال: 2023
ISSN: ['1556-5068']
DOI: https://doi.org/10.2139/ssrn.4318396