منابع مشابه
Research Resources for Nuclear Receptor Signaling Pathways.
Nuclear receptor (NR) signaling pathways impact cellular function in a broad variety of tissues in both normal physiology and disease states. The complex tissue-specific biology of these pathways is an enduring impediment to the development of clinical NR small-molecule modulators that combine therapeutically desirable effects in specific target tissues with suppression of off-target effects in...
متن کاملNuclear Receptor Signaling: a home for nuclear receptor and coregulator signaling research
The field of nuclear receptor and coregulator signaling has grown into one of the most active and interdisciplinary in eukaryotic biology. Papers in this field are spread widely across a vast number of journals, which complicates the task of investigators in keeping current with the literature in the field. In 2003, we launched Nuclear Receptor Signaling as an Open Access reviews, perspectives ...
متن کاملResearch Article: Bioaccumulation of different concentrations of Butachlor in the Zebrafish (Danio rerio)
The herbicides used in agriculture threaten aquatic ecosystems and biodiversity on a global scale. There are several reports on the residues of currently used herbicides in the tissues of aquatic organisms. This study aimed to determine the effect of concentration on the accumulation of Butachlor in liver tissue in zebrafish fish exposed to sub-lethal concentrations of the toxin. In this study,...
متن کاملMicrosporidiosis in zebrafish research facilities.
Pseudoloma neurophilia (Microsporidia) is the most common pathogen detected in zebrafish (Danio rerio) from research facilities. The parasite infects the central nervous system and muscle and may be associated with emaciation and skeletal deformities. However, many fish exhibit subclinical infections. Another microsporidium, Pleistophora hyphessobryconis, has recently been detected in a few zeb...
متن کاملNuclear Androgen Receptor Regulates Testes Organization and Oocyte Maturation in Zebrafish.
Androgens act through the nuclear androgen receptor (AR) to regulate gonad differentiation and development. In mice, AR is necessary for spermatogenesis, testis development, and formation of external genitalia in males and oocyte maturation in females. However, the extent to which these phenotypes are conserved in nonmammalian vertebrates is not well understood. Here, we generate zebrafish with...
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ژورنال
عنوان ژورنال: Journal of Molecular Endocrinology
سال: 2017
ISSN: 0952-5041,1479-6813
DOI: 10.1530/jme-17-0031