Nuclear GPS for Interchromosomal Clustering
نویسندگان
چکیده
منابع مشابه
Strategies to regulate transcription factor–mediated gene positioning and interchromosomal clustering at the nuclear periphery
In budding yeast, targeting of active genes to the nuclear pore complex (NPC) and interchromosomal clustering is mediated by transcription factor (TF) binding sites in the gene promoters. For example, the binding sites for the TFs Put3, Ste12, and Gcn4 are necessary and sufficient to promote positioning at the nuclear periphery and interchromosomal clustering. However, in all three cases, gene ...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2012
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2012.05.019