Nrf2 Signaling Contributes to the Neuroprotective Effects of Urate against 6-OHDA Toxicity
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چکیده
منابع مشابه
Nrf2 Signaling Contributes to the Neuroprotective Effects of Urate against 6-OHDA Toxicity
BACKGROUND Mounting evidence shows that urate may become a biomarker of Parkinson's disease (PD) diagnosis and prognosis and a neuroprotectant candidate for PD therapy. However, the cellular and molecular mechanisms underlying its neuroprotective actions remain poorly understood. RESULTS In this study, we showed that urate pretreatment protected dopaminergic cell line (SH-SY5Y and MES23.5) ag...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0100286