Nrf2-Mediated Metabolic Reprogramming in Cancer
نویسندگان
چکیده
منابع مشابه
Oxygen availability and metabolic reprogramming in cancer.
Hypoxia and dysregulated metabolism are defining features of solid tumors. How cancer cells adapt to low O2 has been illuminated by numerous studies, with "reprogrammed" metabolism being one of the most important mechanisms. This metabolic reprogramming not only promotes cancer cell plasticity, but also provides novel insights for treatment strategies. As the most studied O2 "sensor," hypoxia-i...
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a:4:{s:10:"Background";s:1707:"Early embryonic development in mammals begins in transcriptional silence with an oocyte-mediated transcriptional reprogramming of parental gametes occurs during a so called across-the-board process of “erase-and-rebuild”. In this process, the parental transcription programs are erased long before (maternal) or soon thereafter (paternal) fertilization to generate a...
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ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2018
ISSN: 1942-0900,1942-0994
DOI: 10.1155/2018/9304091