Now That Renal Denervation Works, How Do We Proceed?

Adhesive small bowel obstruction: where do we stand now?

Adhesive small bowel obstruction (ASBO) is one of the most frequently encountered disorders in Emergency Surgery Departments worldwide without negligible hospital admission rates and social costs (1,2). Notwithstanding significant improvements in techniques and materials, intra-abdominal adhesions following abdominal surgery still represent a major unsolved and debated issue harbouring challeng...

The Battle Against COVID-19: Where Do We Stand Now?

Renal denervation – where do we stand in 2014?

Recently, resistant hypertension has received a significant amount of attention, due to its high prevalence among treated hypertensive patients as well as controversies regarding appropriate diagnostics and the development of successful treatment methods. Current results suggest that patients with resistant hypertension are at a higher risk of cardiovascular events and end-organ damage compared...

What do we (not) know about how paracetamol (acetaminophen) works?

WHAT IS KNOWN AND BACKGROUND Although paracetamol (acetaminophen), N-(4-Hydroxyphenyl)acetamide, is one of the world's most widely used analgesics, the mechanism by which it produces its analgesic effect is largely unknown. This lack is relevant because: (i) optimal pain treatment matches the analgesic mechanism to the (patho)physiology of the pain and (ii) modern drug discovery relies on an ap...

Can we do it? Creating health care that works.