Novispirin G10-Induced Lung Toxicity in a Klebsiella pneumoniae InfectionModel
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چکیده
منابع مشابه
Activity of novispirin G10 against Pseudomonas aeruginosa in vitro and in infected burns.
The emergence of multidrug-resistant microbes has serious implications for managing infection and sepsis and has stimulated efforts to develop alternative treatments, such as antimicrobial peptides. The objective of this study was to test a designer peptide, novispirin G10, against multidrug-resistant microorganisms. By two-stage radial diffusion assays, its activity against such organisms comp...
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To The Editor: Monomicrobial liver abscesses caused by Klebsiella pneumoniae are an emerging problem in Asia. Among 77 capsular types of Klebsiella spp., K1 and K2 are the most virulent (1–3). In Asia, isolated strains are mainly serotype K1, followed by K2. In Taiwan, about 63.4% of liver abscesses caused by K. pneu-moniae are associated with K1 strains and 14.2% by K2 (4); no comparable epide...
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Seven cases of lung abscess involving Klebsiella pneumoniae with or without other pathogens presented with gross expansion of the involved lobes or segments and severe clinical illness despite medical treatment. Operative management by rib resection and tube drainage was successful in each case, one of which was found to be an infected cryptococcoma. Postoperative bronchograms were made in six ...
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INTRODUCTION Curcumin, a polyphenol derived from the herb Curcuma longa, has number of antioxidant, anti-inflammatory, antimicrobial, and anti-carcinogenic activities. Its anti-inflammatory property was here studied alone and in combination with clarithromycin in a mouse model of acute inflammation. METHODOLOGY A total of 80 mice divided into four groups were used. Mice receiving curcumin and/...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2003
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.47.12.3901-3906.2003