NOVEL TOPICAL ANTI-AGING HERBAL COMPOSITION

Objective: Anti-aging formulations are among the premier skin care products in global market that huge demand. Different treatments available to slow down aging, but very expensive and often found produce adverse reactions prolong use. Hence, present study has been designed formulate poly herbal anti-aging their evaluation thereon.
 Methods: cream, gel serum were prepared using two medicinal plants Hippophae salicifolia Celosia argentea along with three bioactives caffeine, rutin bakuchiol. The evaluated for physicochemical parameters like pH, texture analysis, acid value, short-term stability study, etc. Phenolics flavanoid content determined. potential was gauged by silico studies glide tool of ‘Schrodinger’.
 Results: Cream, showed good physical appearance free from gritty particles smooth texture. Accelerated indicated insignificant changes formulations. Based on docking score interaction amino acid, compounds plant extracts bioactive activity.
 Conclusion: be stable exhibited as an combination. So, they can used effective combination protect aging.