Novel synthesis of highly functionalized cyclopentane derivatives via [3 + 2] cycloaddition reactions of donor–acceptor cyclopropanes and (E)-3-aryl-2-cyanoacrylates
نویسندگان
چکیده
منابع مشابه
A novel synthesis of (E)-3-methylthio-3-substituted arylamino-2-cyanoacrylates under microwave irradiation.
A facile synthesis of 3-methylthio-3-arylamino-2-cyanoacrylates from 3,3-dimethylthioacrylate and aromatic amines or amino pyridines has been achieved in moderate to high yields (64.0% ~ 93.5%) in 30 minutes at 50 degrees C under microwave irradiation. This method is very simple and the reaction conditions are mild, environmentally friendly and more importantly, quick. In the 3-(4,5-dimethylthi...
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synthesis of some new monocyclic β-lactams containing a quaternary carbon center via a [2+2]cycloaddition reaction is described. the reaction of achiral diphenyl ketene with chiral aldimines derivedfrom chiral 2, 3, 4, 6-tetra-o-acetyl-β-d-galactopyranosylamine, 2, 3, 4, 6-tetra-o-acetyl-β-dglucopyranosylamine and different benzaldehydes resulted in the formation of β-lactams as singlediastereo...
متن کاملEfficient synthesis of arylaminotetrazoles as via [2+3] cycloaddition of nitriles and sodium azide via solid acid catalysis
The [3+2] cycloaddition between various nitriles and sodium azide proceeds smoothly in the presence of zeolite and sulfated Zircona as effective catalyst and in the water and DMF/MeOH, to give the corresponding arylaminotetrazoles in good to high yields. The reaction most probably precedes through the in situ formation of a catalyst azide species, followed by a successive [3+2] cycloaddition wi...
متن کاملAn efficient synthesis of arylaminotetrazoles as via [2+3] cycloaddition of nitriles and sodium azide via solid acid catalysis
The [3+2] cycloaddition between various nitriles and sodium azide proceeds smoothly in the presence of zeolite and sulfated Zircona as effective catalyst and in the water and DMF/MeOH, to give the corresponding arylaminotetrazoles in good to high yields. The reaction most probably precedes through the in situ formation of a catalyst azide species, followed by a successive [3+2] cycloaddition wi...
متن کاملSynthesis and Cytotoxic Evaluation of Novel 3-Substituted Derivatives of 2-Indolinone
The assessment of the degree or rate of cellular proliferation and cell viability is critical for the assessment of the effects of drugs on both normal and malignant cell populations. In the present study, a few novel 3-substituted derivatives of 2-indolinones were synthesized by condensation of substituted oxindole or isatin derivatives with appropriate aldehydes or primary aromatic amine...
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ژورنال
عنوان ژورنال: Journal of Chemical Research
سال: 2019
ISSN: 1747-5198,2047-6507
DOI: 10.1177/1747519819831883