Novel Synthesis of (+)-4-Acetoxy-3-hydroxyethyl-2-azetidinone from Carbohydrate. A Formal Total Synthesis of (+)-Thiehamycin.
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چکیده
منابع مشابه
SYNTHESIS OF OXAZOLO [3, 2-b] 1, 2, 4- TRIAZINES A NOVEL HETEROCYCLIC SYSTEM
The synthesis of 6- methyl- 2- phenyl- 7H- oxazolo [3,2-b] 1,2,4-Triazine- 7-one (6, R=Ph) and its 2-P- bromophenyl analogue to the two members of a new heterocyclic system is described
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کاتالیست یک سنتز جدید برای تیواترها توصیف شده است. واکنش الکل ها با آریل، هتروآریل و آلکیل تیو ل ها درحضور 1،3،5- تری آزو- 2،4،6- تری فسفرین-2،2،4،4،6،6 هگزاکلراید ((tapc به عنوان یک کاتالیست موُثر، بازده های خوب تا عالی از تیواترها را حاصل می کند. علاوه براین، واکنش تحت شرایط بدون فلز و بدون حلال پیش می رود، بنابراین یک مکمل جالب برای روش های شناخته شده سنتز تیواترها ارائه می دهد. یک مکانیسم ا...
15 صفحه اولA Formal Total Synthesis of (2)-Cephalotaxine
thesis of cephalotaxine (1), the major alkaloid of the Cephalotaxus species, because of its unique structural features and antileukemic activity of its ester derivatives, harringtonine (2) and homoharringtonine (3). So far, eight total syntheses of (6)-1 including ours have been reported and the synthesis of (2)-1 has recently been achieved by Mori’s and Nagasaka’s groups. As a part of our own ...
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A new series of N-[2-(1H-1,2,3-benzotriazol-1-yl)ethyl]-4-(substitutedphenyl)-3-chloro-2-oxo-1-iminoazetidine, compounds 4(a-j) were synthesized. The structures of all the synthesized compounds were confirmed by chemical and spectral analyses such as IR, 1H NMR, 13C NMR and FAB-Mass. The compounds 4(a-j) were screened for their antibacterial, antifungal and antitubercular activities and gave ac...
متن کاملSynthesis and Characterization of Novel 4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives from Diazomethane and HCl
Reaction of thionyl chloride with 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4- oxoquinoline-3-carboxylic acid 1 gave acid chloride 2. Compound 2 was reacted with glycine and D-glutamic acid to afford 2-(7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4- dihydroquinoline-3-carbonyl) aminopantandioicacid 3a and 2-(7-chloro-1-cyclopropyl-6- fluoro -4- oxo-1,4-dihydroquinoline-3-carbonyl)aminoacetica...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 2000
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.53.1231