Novel structure of hepatic extracellular matrices containing arylsulfatase A
نویسندگان
چکیده
منابع مشابه
Arylsulfatase K, a novel lysosomal sulfatase.
The human sulfatase family has 17 members, 13 of which have been characterized biochemically. These enzymes specifically hydrolyze sulfate esters in glycosaminoglycans, sulfolipids, or steroid sulfates, thereby playing key roles in cellular degradation, cell signaling, and hormone regulation. The loss of sulfatase activity has been linked to severe pathophysiological conditions such as lysosoma...
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Background: Mucopolysaccharidosis type-VI (MPS-VI), which is inherited as an autosomal recessive trait, results from the deficiency of N-acetylgalactosamine 4-sulfatase (arylsulfatase B) activity and the lysosomal accumulation of dermatan sulfate. In this study, ARSB mutation analysis was performed on three unrelated patients who were originally from the West Azerbaijan province of Iran. Method...
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ژورنال
عنوان ژورنال: Okajimas Folia Anatomica Japonica
سال: 2013
ISSN: 0030-154X,1881-1736
DOI: 10.2535/ofaj.90.17