Novel polymorphisms in human macrophage inflammatory protein-1 alpha (MIP-1α) gene
نویسندگان
چکیده
منابع مشابه
Role of macrophage inflammatory protein (MIP)-1α/CCL3 in leukemogenesis
The biologic function of the CC chemokine macrophage inflammatory protein-1α (MIP-1α/CCL3) has been extensively studied since its initial identification as a macrophage-derived inflammatory mediator. In addition to its proinflammatory activities, CCL3 negatively regulates the proliferation of hematopoietic stem/progenitor cells (HSPCs). On the basis of this unique function, CCL3 is alternativel...
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Lymphocyte trafficking is an essential process in immune and inflammatory functions which can be thought to contain at least two main components: adhesion and migration. Whereas adhesion molecules such as the sdectins are known to mediate the homing of leukocytes from the blood to the endothelium, the chemoattractant substances responsible for the migration of specific subsets of lymphocytes to...
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متن کاملCorrelation of macrophage inflammatory protein-1α single gene polymorphisms with the susceptibility to pigeon breeder's lung in chinese uygur population.
OBJECTIVE To investigate the correlation of macrophage inflammatory protein-1α (MIP-1α) gene single nucleotide polymorphisms (SNP) with the susceptibility to pigeon breeder's lung (PBL) in Chinese Uygur population. METHODS A total of 92 Uygur from Xinjiang, China were enrolled in the study. Among them, there were 32 patients with PBL, 30 negative controls with history of exposure to pigeons a...
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ژورنال
عنوان ژورنال: Genes & Immunity
سال: 2001
ISSN: 1466-4879,1476-5470
DOI: 10.1038/sj.gene.6363759