Novel Non-PEG Derived Polyethers as Solid Supports. 2. Solid-Phase Synthesis Studies
نویسندگان
چکیده
منابع مشابه
Solid-Phase Synthesis on Planar Supports
Planar supports represent a unique opportunity in designing novel approaches to solid-phase synthesis of peptides and small organic molecules. Published work includes assembly on cellulose paper sheets, cotton strips, or membranes, as well as ultrahigh-density synthesis on glass supports. Planar carriers allow for the synthesis to be performed without any reaction vessels (inclusion volume chem...
متن کاملBiopolymer Synthesis on Solid Supports
The concept of solid phase synthesis began as a new approach to the preparation of peptides, but has been extended to the synthesis of polynucleotides, polysaccharides, polyamides and a variety of other classes of compounds. The solid support simplifies and accelerates the synthetic process, aids the separation of reagents and by-products, and reduces problems of insolubility of intermediates. ...
متن کاملSolid phase synthesis.
The proteins, as the Greek root of their name implies, are of first rank in living systems, and their smaller relatives, the peptides, have now also been discovered to have important roles in biology. Among their members are many of the hormones, releasing factors, growth factors, ion carriers, antibiotics, toxins, and neuropeptides. My purpose today is to describe the chemical synthesis of pep...
متن کاملPorous silicon-based nanostructured microparticles as degradable supports for solid-phase synthesis and release of oligonucleotides
We describe the preparation of several types of porous silicon (pSi) microparticles as supports for the solid-phase synthesis of oligonucleotides. The first of these supports facilitates oligonucleotide release from the nanostructured support during the oligonucleotide deprotection step, while the second type of support is able to withstand the cleavage and deprotection of the oligonucleotides ...
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ژورنال
عنوان ژورنال: Journal of Combinatorial Chemistry
سال: 2007
ISSN: 1520-4766,1520-4774
DOI: 10.1021/cc7000887