Novel Nano-Sized MR Contrast Agent Mediates Strong Tumor Contrast Enhancement in an Oncogene-Driven Breast Cancer Model
نویسندگان
چکیده
منابع مشابه
Novel Nano-Sized MR Contrast Agent Mediates Strong Tumor Contrast Enhancement in an Oncogene-Driven Breast Cancer Model
The current study was carried out to test the potential of a new nanomaterial (Spago Pix) as a macromolecular magnetic MR contrast agent for tumor detection and to verify the presence of nanomaterial in tumor tissue. Spago Pix, synthesized by Spago Nanomedical AB, is a nanomaterial with a globular shape, an average hydrodynamic diameter of 5 nm, and a relaxivity (r1) of approximately 30 (mM Mn)...
متن کاملRecent Advances in PET-MR Hybrid contrast agent
Introduction: All of the Imaging modalities have advantages and disadvantages alone. So if we want to have the best and perfect image, combining these modalities produces something we desired. PET-MR images consist of morphologic and metabolic data. MRI and PET provide high spatial and contrast resolution and high sensitivity and molecular information respectively. Hybrid PET-...
متن کاملA novel iron oxide contrast agent: Nano in size and functioning as micron-sized particles
INTRODUCTION MR cellular imaging using iron-oxide-based contrast agents is an attractive technique in cell tracking and monitoring cell therapies. However, one major obstacle of the widespread application of this technique in clinics is the low sensitivity inherently associated with MRI. Therefore, there are a lot of efforts aimed at enhancing the susceptibility effect induced by the iron-oxide...
متن کاملA novel MRI contrast agent synthesized by ion exchange method
Objective: In this study, the zeolite-coated iron oxide nanoparticles were evaluated as MRI contrast agent and effect of the nanocomposite synthesis method on MRI contrast was tested. Materials and Methods: Ion exchange method was used for synthesis of iron oxide-zeolite and the as prepared nanocomposite was characterized by XRD, FESEM and TEM. The nanocomposite toxicity in the cell culture, a...
متن کاملDIFFUSE CONTRAST ENHANCEMENT ON MR IMAGES IN BRAIN INFARCTION: \"PSEUDOTUMOR SIGN\"
The purpose of this study was to describe the pattern of diffuse enhancement seen on contrast-enhanced MR images in patients with subacute infarction. A retrospective study of 104 patients with the diagnosis of stroke who had undergone contrast-enhanced MR scanning within2 weeks of the inciting neurological event revealed 66 patients who demonstrated different patterns of contrast-enhanceme...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0107762