NOVEL MULTIPARTICULATE DRUG DELIVERY SYSTEM OF CARVEDILOL AS ANTIHYPERTENSIVE DRUG

Multiparticulate chitosan-dispersed system for drug delivery.

A multiparticulate chitosan-dispersed system (CDS), which is composed of the drug reservoir and the drug release-regulating layer, was developed for drug delivery. The drug release-regulating layer is a mixture of water-insoluble polymer and chitosan powder. The drug is released from CDS pellets in all regions of the gastrointestinal tract (from the stomach to the colon). CDS pellets containing...

Multiparticulate Carriers for Controlled Oral Drug Delivery

An overview on multiparticulate drug delivery system: Pellets

Pellets can be defined as small, free flowing, spherical or semi-spherical solid units, typically from about 0.5 mm to 1.5 mm, and intended usually for oral administration, manufactured by the agglomerates of fine powders or granules of bulk drugs and excipients using appropriate processing equipment. Pellets can be prepared by many methods, the compaction and drug-layering being the most widel...

Novel transdermal drug delivery systems

Background and aim: Eczema is a common inflammatory skin disease. Although history and physical examination are important in diagnosis of allergen, because of extent of environmental allergens, those are not simply recognized. The objective of this study was to determine allergens in patients with contact or atopic dermatitis referred to Razi hospital.Materials and Meth...

Multiparticulate formulation approach to colon specific drug delivery: current perspectives.

Colon specific drug delivery has gained increased importance not just for the delivery of drugs for the treatment of local diseases associated with the colon but also as potential site for the systemic delivery of therapeutic peptide and proteins. To achieve successful colon targeted drug delivery, a drug needs to be protected from degradation, release and/or absorption in the upper portion of ...