Novel iridium (III)‑derived organometallic compound for the inhibition of human platelet activation
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چکیده
منابع مشابه
Novel iridium (III)-derived organometallic compound for the inhibition of human platelet activation
Since cisplatin achieved clinical success, transition metal platinum (Pt) drugs have been effectively used for the treatment of cancer. Iridium (Ir) compounds are considered to be potential alternatives to Pt compounds, as they possess promising anticancer effects with minor side effects. Platelet activation is associated with the metastasis and progression of cancer, and also with arterial thr...
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15 صفحه اولNew Therapeutic Agent against Arterial Thrombosis: An Iridium(III)-Derived Organometallic Compound
Platelet activation plays a major role in cardio and cerebrovascular diseases, and cancer progression. Disruption of platelet activation represents an attractive therapeutic target for reducing the bidirectional cross talk between platelets and tumor cells. Platinum (Pt) compounds have been used for treating cancer. Hence, replacing Pt with iridium (Ir) is considered a potential alternative. We...
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ژورنال
عنوان ژورنال: International Journal of Molecular Medicine
سال: 2018
ISSN: 1107-3756,1791-244X
DOI: 10.3892/ijmm.2018.3472