Novel immunosuppressive agents in kidney transplantation
نویسندگان
چکیده
منابع مشابه
Immunosuppressive drugs for kidney transplantation.
N Engl J Med 2004;351:2715-29. Copyright © 2004 Massachusetts Medical Society. he central issue in organ transplantation remains suppression of allograft rejection. Thus, development of immunosuppressive drugs is the key to successful allograft function. Immunosuppressive agents are used for induction (intense immunosuppression in the initial days after transplantation), maintenance, and revers...
متن کاملState of immunosuppressive agents in organ transplantation.
TRANSPLANT A nON has been built on the foundation of using drug thera.py to nonspecifically suppress the recipient immune response. Failure to achieve adequate immunosuppression is associated with a high incidence of graft loss from rejection. The present goal of immunosuppressive regimens is to suppress the immune response to the allograft while preserving sufficient immunity to avoid opportun...
متن کاملModern Immunosuppressive Therapy in Kidney Transplantation
Immunosuppressive therapy is a key component for successful kidney transplantation. It is commonly believed that more intensive immunosuppression is needed initially to prevent rejection episodes and less immunosuppression is subsequently maintained to minimize the overall risk of infection and malignancy. The selection of drugs should be guided by a comprehensive assessment of the immunologic ...
متن کاملKidney Transplantation in Iran
Kidney transplantation in patients with end stage renal disease is preferred to dialysis because transplantation provides a better quality of life andimproved survival. However, the gap between the supply and demand for a renal allograft is widening and the waiting time is increasing. Iranian protocol, a controlled transplant program supported by the government for living unrelated donors, was ...
متن کاملImmunosuppressive therapy protocols in kidney transplantation in adults.
In practical terms, regardless of HLA compatibility level, whenever tissues are transplanted from one person to another it is essential to suppress the immune response of the recipient. A variety of methods are available however, the most frequently used ones have the disadvantage of being immunologicaly non specific. The consequence is a difficult balance between immunosuppression sufficient t...
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ژورنال
عنوان ژورنال: World Journal of Transplantation
سال: 2013
ISSN: 2220-3230
DOI: 10.5500/wjt.v3.i4.68