Novel Human Herpesvirus 8 Subtype D Strains in Vanuatu, Melanesia
نویسندگان
چکیده
منابع مشابه
Novel Human Herpesvirus 8 Subtype D Strains in Vanuatu, Melanesia
We show human herpesvirus 8 with diverse molecular subtype D variants to be highly endemic among the Ni-Vanuatu population. Most K1 genes were nearly identical to Polynesian strains, although a few clustered with Australian or Taiwanese strains. These results suggest diverse origins of the Ni-Vanuatu population and raise questions about the ancient human population movements in Melanesia.
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Department of Allergy and Immunology, Saitama Medical School, Saitama 350-0495; Department of International Affairs and Tropical Medicine, Tokyo Women’s Medical University, School of Medicine, Tokyo 162-8666; Department of Public Health, Kyorin University School of Medicine, Tokyo 181-8611; Department of Pathology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan; and Department...
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Four of 391 Ni-Vanuatu women were infected with variants of human T-cell leukemia virus type 1 (HTLV-1) Melanesian subtype C. These strains had env nucleotide sequences approximately 99% similar to each other and diverging from the main molecular subtypes of HTLV-1 by 6% to 9%. These strains were likely introduced during ancient human population movements in Melanesia.
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Human herpesvirus 8 (HHV-8), a gammaherpesvirus implicated in Kaposi's sarcoma, primary effusion lymphoma, and Castleman's disease, encodes several pathogenically important cellular homologs. To define the HHV-8 transcription program, RNA obtained from latently infected body cavity-based lymphoma 1 cells induced to undergo lytic replication was used to query a custom HHV-8 DNA microarray contai...
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 2007
ISSN: 1080-6040,1080-6059
DOI: 10.3201/eid1311.070636