Novel Genetic Mutations in a Sporadic Port-Wine Stain

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Novel genetic mutations in a sporadic port-wine stain.

IMPORTANCE Port-wine stains (PWSs) are common congenital cutaneous capillary malformations. A somatic GNAQ mutation was recently identified in patients with sporadic PWSs and Sturge-Weber syndrome. However, subsequent studies to confirm or extend this observation are lacking.OBSERVATIONS We report a long-standing, unilateral facial PWS of a man in his early 70s confirmed by histopathological an...

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A Comparison of Acquired Port-wine Stain with Congenital Port-wine Stain Using an Image Analyzer.

BACKGROUND Recent reports have proposed that there were no differences between acquired port-wine stain (APWS) and congenital port-wine stain (CPWS) except the onset of disease. Pulsed dye laser (PDL) therapy is regarded as the treatment of choice in PWS. Although in some articles, APWS might have shown a better response to PDL than CPWS, this is still controversial. It has been assumed however...

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Acquired Port-Wine stain: Report of two cases

Acquired port-wine stain is a rare vascular lesion that mimics a congenital port-wine stain clinically and histologically, but is acquired after birth. A survey on more than 60 reported cases in the literature reveals that most of these cases are idiopathic, but some of the cases developed after physical or mechanical trauma, hormonal changes, chronic sun exposure, and medications (OCP, i...

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Port-wine stain laser treatments and novel approaches.

BACKGROUND AND OBJECTIVES Port-wine stains (PWSs) are capillary vascular malformations that are commonly resistant to treatment. Currently, the pulsed dye laser (PDL) is the treatment of choice. Multiple treatments are required and complete blanching after laser irradiation is rarely achieved. We review current therapeutic modalities for PWSs and recent developments for enhanced clearance. ST...

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ژورنال

عنوان ژورنال: JAMA Dermatology

سال: 2014

ISSN: 2168-6068

DOI: 10.1001/jamadermatol.2014.1244