Novel fibrin-fibronectin matrix accelerates mice skin wound healing
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چکیده
منابع مشابه
Reduced FOXO1 expression accelerates skin wound healing and attenuates scarring.
The forkhead box O (FOXO) family has been extensively investigated in aging and metabolism, but its role in tissue-repair processes remains largely unknown. Herein, we clarify the molecular aspect of the FOXO family in skin wound healing. We demonstrated that Foxo1 and Foxo3a were both up-regulated during murine skin wound healing. Partial knockout of Foxo1 in Foxo1(+/-) mice throughout the bod...
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Skin wound healing is a natural and intricate process that takes place after injury, involving different sequential phases such as hemostasis, inflammatory phase, proliferative phase, and remodeling that are associated with complex biochemical events. The interruption or failure of wound healing leads to chronic nonhealing wounds or fibrosis-associated diseases constituting a major health probl...
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Craniofacial Developmental Biology and Regeneration Branch, National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland, U.S.A.; *Center for Combat Casualty and Life Sustainment Research, Department of Pathology, USUHS, Bethesda, Maryland, U.S.A.; †Department of Biochemistry and Molecular Biology, The George Washington University School of Medicine and Health Sciences, Washi...
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The antagonism of CXC-chemokine receptor 4 (CXCR4) with AMD3100 improves cardiac performance after myocardial infarction by augmenting the recruitment of endothelial progenitor cells (EPCs) from the bone marrow to the regenerating vasculature. We investigated whether AMD3100 may accelerate diabetes-impaired wound healing through a similar mechanism. Skin wounds were made on the backs of leptin ...
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ژورنال
عنوان ژورنال: Bioactive Materials
سال: 2020
ISSN: 2452-199X
DOI: 10.1016/j.bioactmat.2020.06.015