Novel Case of Metastatic Testicular Immature Teratoma Invading the Duodenum

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Novel Case of Metastatic Testicular Immature Teratoma Invading the Duodenum

We present the first report of an immature teratoma arising from a germ cell testicular cancer invading the duodenum. While other seminomatous and non-seminomatous germ cell tumors are known to metastasize to the duodenum, this is the first such case involving an immature teratoma directly invading the duodenum from a metastatic retroperitoneal mass.

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Introduction: Teratomas are neoplastic tumors derived from totipotent germ cells containing a wide assortment of tissues originating from all three germ cell layers. Teratomas can be mature or immature depending on the presence of immature tissues; typically neuroepithelial tissue. Immature teratomas can be oncologically benign or malignant, and can be divided into three grades with increasingl...

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Salvage combination chemotherapy with docetaxel, ifosfamide and cisplatin (DIP): successful treatment of a case with metastatic testicular immature teratoma.

We present a case of metastatic testicular immature teratoma that was successfully treated despite resistance to standard chemotherapy and unsuccessful salvage surgery. At first, BEP (bleomycin, etoposide and cisplatin) treatment was performed but failed. The patient underwent incomplete retroperitoneal lymph node dissection. He was then referred to us. By the time of the referral lung and medi...

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Metastatic teratoma from a regressed impalpable testicular primary.

A young man presented with a perineal tumour which despite intensive investigation, remained of unknown origin and required radical excision. It was subsequently shown to be a metastasis from a primary regressed testicular teratoma. It is important to exclude a testicular origin in these patients wherever possible because such tumours are often chemosensitive.

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Pure Testicular Teratoma Presenting as a Metastatic Germ Cell Tumor

Mature teratoma comprises 5-10 % of all testicular neoplasms. Pure testicular teratoma is rare in adulthood with an incidence of 5 %. Regardless of differentiation postpubertal testicular teratoma have aggressive behavior and microscopic appearance of metastasis may differ from that of the primary. We present a case of pure teratoma of testis in an adult presenting as a metastatic germ cell tumor.

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ژورنال

عنوان ژورنال: The Open Surgical Oncology Journal

سال: 2009

ISSN: 1876-5041

DOI: 10.2174/1876504100901010016