Novel biochemical prognostic indicators in COVID-19: Can CRP/albumin, urea/albumin, and LDH/albumin ratios be used to predict mortality and length of hospitalization?

Objective: As the coronavirus disease 2019 (COVID-19) pandemic continues, clinical and laboratory predictors of progression to serious lethal types illness are urgently needed. We aimed investigate how well hematologic, biochemical, immunologic biomarkers could distinguish between patients with without severe or fatal COVID-19. Material Methods: This retrospective study was performed in internal medicine departments two institutions. Data were collected from hospital database, medical files 280 adult COVID-19 reviewed. The relationship hematologic biochemical parameters which include C-reactive protein (CRP)/albumin, urea/albumin, lactate dehydrogenase (LDH)/albumin ratios length hospitalization, severity, survival investigated. Results: Our series consisted (147 women, 133 men) an average age 58.34 ± 18.64 (range: 19 93). Most (n=171, 61.1%) had mild-moderate disease, while diagnosed 109 cases (38.9%). A total 36 died due yielding a mortality rate 12.9%. hospitalization 8.98 5.80 days 1-55 days). noted that significantly associated severity mortality, hospitalization. Conclusion: Several have been established help risk stratification models for predicting results infection. suggest clinicians closely track CRP/albumin, LDH/albumin hospitalized respiratory distress as indicators possible critical progression.