Novel Approaches to Combat Medical Device-Associated BioFilms

Biofilms are aggregates formed as a protective survival state by microorganisms to adapt the environment and can be resistant antimicrobial agents host immune responses due chemical or physical diffusion barriers, modified nutrient environments, suppression of growth rate within biofilms, genetic adaptation cells biofilms. With widespread use medical devices, device-associated biofilms continue pose serious threat human health, these have become most important source nosocomial infections. However, traditional cannot completely eliminate New strategies for treatment targeting biofilm infections urgently required. Several novel approaches been developed identified effective promising treatments. In this review, we briefly summarize challenges associated with highlight latest aimed at preventing eradicating