Novel approach to inhibiting chemokine function
نویسندگان
چکیده
منابع مشابه
Novel approach to inhibiting chemokine function
CC chemokine ligand 2 (CCL2) or monocyte chemoattractant protein-1 (MCP-1) is an important chemoattractant for monocytes and macrophages (Deshmane et al, 2009). CCL2 is the main ligand for the chemokine receptor CCR2, which mediates CCL2’s biological activity. CCR2 is a seven transmembrane spanning Gai protein-coupled receptor (GPCR) constitutively expressed at high levels on monocytes and macr...
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ژورنال
عنوان ژورنال: EMBO Molecular Medicine
سال: 2011
ISSN: 1757-4676,1757-4684
DOI: 10.1002/emmm.201100161