Normobaric hyperoxia stimulates superoxide and nitric oxide production in the caudal solitary complex of rat brain slices
نویسندگان
چکیده
منابع مشابه
Effects of preconditioning with intermittent normobaric hyperoxia on TNFR1 and TNFR2 expression in the rat brain
Introduction: Recent studies have shown that intermittent normobaric hyperoxia (HO) protects the rat brain from ischemia reperfusion injury. However, the exact mechanism of this kind of protection in vivo is not known. In this study, the effect of HO on expression of TNFR1 and TNFR2 in a stroke model was investigated. Methods: In this experimental study, rats were divided into 4 groups: no...
متن کاملThe Effect of Normobaric Hyperoxia on Superoxide Dismutase Activity and Neurologic Deficits in Huntington Animal Model
Introduction: resent studies have been shown that normobaric hyperoxia (HO) can induce excitotoxicity and stress oxidative tolerance (ETT) in variety of organs such as brain. In this study, we examined the intermittent dose of normobaric hyperoxia (HO) on neurologic deficit, and superoxide dismutase activity in brain tissue of Huntington animal model. Method: The rats were divided to three...
متن کاملthe study of normobaric hyperoxia preconditioning on superoxide dismutase activity in the rat stroke model
objective: ischemic preconditioning (ipc) is an endogenous phenomenon that can induce ischemic tolerance (it) in variety of organs such as brain. in this study, we examined the intermittent and prolonged normobaric hyperoxia (ho) on neurologic deficit scores, infarct volume, and superoxide dismutase activity. materials and methods: the rats were divided to four main groups. first two main grou...
متن کاملOxygen measurements in brain stem slices exposed to normobaric hyperoxia and hyperbaric oxygen.
We previously reported (J Appl Physiol 89: 807-822, 2000) that < or =10 min of hyperbaric oxygen (HBO(2); < or = 2,468 Torr) stimulates solitary complex neurons. To better define the hyperoxic stimulus, we measured PO(2) in the solitary complex of 300-microm-thick rat medullary slices, using polarographic carbon fiber microelectrodes, during perfusion with media having PO(2) values ranging from...
متن کاملStudy on the effect of neuroprotective prolonged and intermittent normobaric hyperoxia on serum level of TNF-α and glutamate transporters expression in rat brain
Introduction: Prolonged and intermittent oxygen pre-exposure is associated with protection against ischemic reperfusion (IR) injury. In the current study, attempts were made to investigate the relationship between exposure to prolonged and intermittent normobaric hyperoxia (NBHO) and expression of excitatory amino acids transporters (EAATs) and TNF-α level. Method: Rats were divided into fo...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Cell Physiology
سال: 2016
ISSN: 0363-6143,1522-1563
DOI: 10.1152/ajpcell.00160.2016