Normal Villous Architecture With Increased Intraepithelial Lymphocytes
نویسندگان
چکیده
منابع مشابه
The normal range of duodenal intraepithelial lymphocytes.
BACKGROUND Increased duodenal intraepithelial lymphocytes is a key histological finding in celiac disease. Available studies suggest a wide normal range (10 - 40 intraepithelial lymphocytes /100 epithelial cells, EC). We assessed the normal range of distal duodenal intraepithelial lymphocytes. METHODS Biopsies from the normal-looking distal duodenum from individuals referring for endoscopy fo...
متن کامل[Splenic lymphoma with circulating villous lymphocytes].
Splenic lymphoma with circulating villous lymphocytes (SLVL) is a special kind of lymphoproliferative disease characterized by specific clinical, haematological, histomorphological and immunophenotypic features that make it different from hairy cell leukaemia, prolymphocytic leukaemia and non-Hodgkin lymphoma. Four patients suffering from SLVL, 3 men and 1 woman, 62 years in average (range 55-6...
متن کاملSplenic lymphoma with villous lymphocytes (SLVL)
Phenotype/cell stem origin Light chain restriction surface immunoglobulin. Most cases express IgM and IgD. B-cells express CD19+, CD20+, CD22+, CD24+, CD79b+, FMC7+ and DBA44+. Lack expression of CD5 (85%), CD10, CD23, CD103 and CD123. Epidemiology In 1987, the term SLVL was introduced; 1-2% of nonHodgkin lymphomas; occurs in the elderly (med 70 yrs); sex ratio 2M/1F. Clinics Splenomegaly witho...
متن کاملIntraepithelial lymphocytes in the villous tip: do they indicate potential coeliac disease?
BACKGROUND The counting of intraepithelial lymphocytes (IELs) in the villous tips of architecturally normal small bowel biopsy specimens was proposed as a method to measure mucosal infiltration in gluten sensitive patients. AIMS To apply this straightforward method in duodenal biopsy specimens from patients affected by potential coeliac disease (PCD) to verify whether it can discriminate thes...
متن کاملNormal variation in intraepithelial lymphocytes of the terminal ileum.
The number of intraepithelial lymphocytes (IELs) is often increased in the terminal ileum of patients with immune-mediated inflammatory diseases of the colon. However, data regarding their number in normal ileal mucosa of asymptomatic patients are lacking. We aimed to establish the acceptable range of IELs in biopsy specimens of normal ileal mucosa. Ileal mucosal biopsy specimens obtained durin...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2015
ISSN: 1943-7722,0002-9173
DOI: 10.1309/ajcpbkqnd4shvx9q