Normal Values and Associated Factors in High-resolution Anorectal Manometry in Healthy Vietnamese Adults

Abstract Introduction The present study aims to identify normal high-resolution anorectal manometry (HRAM) values and related factors in healthy Vietnamese adults. Methods cross-sectional was conducted at the Viet Duc hospital, Hanoi, Vietnam, during April May 2019. Healthy volunteers were recruited participate study. Anorectal measurement from digestive tract, including pressure, recorded. Results A total of 76 recruited. mean functional anal canal length 4.2 ± 0.5 cm, while high-pressure zone 3.4 cm. defecation index 1.4 0.8, with ranging 0.3 5.0. threshold volume elicit rectoanal inhibitory reflex (RAIR) 18.1 mL. rectal sensation 32.4 mL, 81.6 159 mL for first sensation, desire defecate, urge respectively. Dyssynergic patterns occurred ∼ 50% participants included mainly types I (27.6%) III (14.6%). There significant differences between male female patients terms maximum squeeze cough strain pressure (all p < 0.01). Conclusions establishes HRAM adults, particularly regarding sensation. Further studies that include larger sample sizes should be further confirm constants their relationships.