Normal reproductive organ development in CF-1 mice following prenatal exposure to bisphenol A
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چکیده
منابع مشابه
Normal reproductive organ development in CF-1 mice following prenatal exposure to bisphenol A.
Bisphenol A (BPA) is a monomer used in the manufacture of a multitude of chemical products, including epoxy resins and polycarbonate. The objective of this study was to evaluate the effects of BPA on male sexual development. This study, performed in CF-1 mice, was limited to the measurement of sex-organ weights, daily sperm production (DSP), epididymal sperm count, and testis histopathology in ...
متن کاملNormal Reproductive Organ Development
Bisphenol A (BPA) is a monomer used in the manufacture of a multitude of chemical products, including epoxy resins and polycarbonate. The objective of this study was to evaluate the effects of BPA on male sexual development. This study, performed in CF-1 mice, was limited to the measurement of sex organ weights, daily sperm production (DSP), epididymal sperm count, and testis histopathology in ...
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Type 1 diabetes mellitus (T1DM) is an autoimmune destruction of insulin producing pancreatic beta-cells due to a genetic predisposition and can be triggered by environmental factors. We have previously shown that bisphenol A (BPA) accelerates the spontaneous development of diabetes in non-obese diabetic (NOD) mice. Here, we hypothesized that oral exposure to a mixture of the endocrine disruptor...
متن کاملTransmaternal bisphenol A exposure accelerates diabetes type 1 development in NOD mice.
Diabetes mellitus type 1 is an autoimmune disease with a genetic predisposition that is triggered by environmental factors during early life. Epidemiological studies show that bisphenol A (BPA), an endocrine disruptor, has been detected in about 90% of all analyzed human urine samples. In this study, BPA was found to increase the severity of insulitis and the incidence of diabetes in female non...
متن کامل1 Human Exposure to Bisphenol a ( Bpa )
Acknowedgements: The authors gratefully acknowledge expertise and input from additional panel members: Jane C. Atkinson, Antonia M. Calafat, Frederick Eichmiller, Albert Kingman, Ruthann Rudel, and Kristina A. Thayer. This review was prepared in conjunction with the Bisphenol A Conference, Chapel Hill, NC, November 28-29, 2006. Support was provided by the National Institute of Environmental Hea...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 1999
ISSN: 1096-6080,1096-0929
DOI: 10.1093/toxsci/50.1.36