NORMAL: accurate nucleosome positioning using a modified Gaussian mixture model
نویسندگان
چکیده
منابع مشابه
NOrMAL: accurate nucleosome positioning using a modified Gaussian mixture model
MOTIVATION Nucleosomes are the basic elements of chromatin structure. They control the packaging of DNA and play a critical role in gene regulation by allowing physical access to transcription factors. The advent of second-generation sequencing has enabled landmark genome-wide studies of nucleosome positions for several model organisms. Current methods to determine nucleosome positioning first ...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2012
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/bts206